The aim of this study was to look at how adolescent binge drinking behavior affects white matter in the context of marijuana use. White matter integrity, indexed by FA, differed between groups in eight clusters located in both association fiber pathways (e.g., fronto-occipital fasciculus, superior longitudinal fasciculus) as well as the corona radiata. These particular association and projection white matter fiber tracts, often implicated in neurocognitive functioning in both adults and children, continue to develop throughout adolescence and are considered important for connecting sensory structures to the frontal lobes [8,10,52,79,99,103,104].
