Data were from the COGA study (Edenberg, 2002). COGA is a diverse, multi-site, multi-generational, family-based study of genetic and environmental factors for alcohol use disorders (Begleiter et al., 1995, Reich et al., 1998). Families with multiple members with alcohol use disorders and community-based comparison families were recruited into the study and have been followed for over 30 years. The Institutional Review Board at all sites approved this study and written consent/assent was obtained from all participants. The present study includes all data available (originally recruited family members and offspring from the original COGA study, the COGA prospective study, and the COGA Interactive Research Project Grant study) for individuals ages 12 to 32 who met the following criteria (1) had GWAS data available, (2) completed the adolescent or adult Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) Interview (Bucholz et al., 1994), and (3) had electrophysiological data available collected at the time of a complete interview. This resulted in a total sample of 2851 EA individuals and 1402 AA individuals. Sample descriptions are included in Table 1.
