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Chunk #30 — Discussion

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Genome wide association for substance dependence: convergent results from epidemiologic and research volunteer samples.
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A number of the genes identified in this work are also identified in genome wide association and/or candidate gene datasets for heritable disorders or phenotypes that co-occur with addictions. As we discuss elsewhere, dependence-vulnerability GWA results overlap at levels greater than expected by chance with GWA studies of cognitive abilities, personality features, frontal lobe brain volumes and bipolar disorder [13].