Chunk #26 — Results

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SNP-based pathway enrichment analysis for genome-wide association studies.

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Relaxing the nominal P-value cut-off to 0.01, with FDR q-value controlled within 10%, resulted in 40 significant pathways detection in EA data set, and 27 significant pathways in AA data set. Among them, 17 pathways are shared (Monte Carlo simulation P-value for sharing is less than 1.0e-6). The full list of 17 shared pathways is shown in Table 2.