Having shown that ~1% of variants can account for the majority of heritability attributable to common variation, we next considered whether the expanded set of height-associated variants could be used to identify the genomic features and biological pathways of most relevance to normal variation in adult height. To test whether our GWAS could implicate new biology, we used established and novel approaches to test whether the height-associated loci were enriched for functionally relevant variants, genes, pathways, and tissues.
