of Z scores in Table 1). In addition to the SNPs shown in Table 1, a further interesting association is with rs11030064 (P = 8.05 × 10−5), a SNP lying close to the brain-derived neurotrophic factor (BDNF) gene, and an association was also found with the extensively studied variation at Val66Met (rs6265; P = 0.0016). Several signals were also seen in the region of RAB3GAP1 (rs16831315; P = 8.05 × 10−5), which encodes a protein implicated in the exocytosis of neurotransmitters and hormones; in GFRA1, the gene for a glial cell line-derived neurotrophic factor, (rs4562724; P = 9.45 × 10−5); and in DCAMKL1 (rs17786591; P = 2.97 × 10−5), encoding a doublecortin and CaM kinase-like protein.
