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Chunk #0 — Introduction

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Recent advances in genetic studies of alcohol use disorders.
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Alcohol use disorder (AUD) is one of the most common and costly public health problems in the United States and throughout the world[1, 2]. A person with AUD consumes alcohol in quantities that might be injurious to themselves and to people around them[2, 3]. Infect, the physical and mental health issues associated with excessive consumption of alcohol are known for centuries. Worldwide, an estimated 20–30% cases of esophageal cancer, liver cancer, cirrhosis of the liver, homicide, epilepsy, and motor vehicle accidents can be attributed to excessive consumption of alcohol[4].