Chunk #13 — Materials and Methods — Co-expression Analysis of RGMA

Source

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.

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A novel bioinformatics pipeline was developed to search and prioritize genes co-expressed with RGMA in an unbiased way genome-wide. The correlations identified between RGMA and the identified co-expressed genes were subject to validation in brain tissue samples (n=1301) downloaded from GEO (see RGMA Co-Expression Analysis in Supplementary Information).