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Chunk #0 — Introduction

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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
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In 2012, 5.9% of all global deaths were attributable to alcohol and roughly a quarter of all deaths in the 20–39-year-age group.1 Over 200 diseases are linked to alcohol consumption and the proportion of the global disease burden, measured in disability-adjusted life years, is over 5%.1 Almost a quarter of disability-adjusted life years attributable to alcohol consumption were the result of neuropsychiatric disorders such as alcohol use disorders (AUD) and major depressive disorder.2