The ERV balances the strength of the genetic signal for the endophenotype and the strength of its relation to the disorder of interest. It is defined using the square-root of the heritability of the illness (h i 2), the square-root of the heritability of the endophenotype (h e 2), and their genetic correlation (ρg):\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ {\mathrm{ERV}}_{\mathrm{i}\mathrm{e}}=\left|\surd {h_{\mathrm{i}}}^2\kern1em \surd {h_{\mathrm{e}}}^2{\rho}_{\mathrm{g}}\right|. $$\end{document}ERVie=√hi2√he2ρg.
