Chunk #78 — Figure 4

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Power and predictive accuracy of polygenic risk scores.

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AUC as a function of sample size, using a panel of 1,000,000 markers that explains the full heritability. n, number of cases and of controls in training sample. Heritability of liability, 76% for Crohn's disease. 44% for breast cancer. Line annotations are the proportion of markers with no effect on disease.