Bootstrapping estimation using 5,000 resamples was used to test mediational models by which level of response to alcohol (i.e., SRE-T) mediated the effects of SNP rs1497571 of the GABRG1 gene on average number of drinks per episode (ACQ1), maximum number of drinks in a drinking episode (ACQ2), and score on the AUDIT. Results, however, did not support the mediational models for ACQ1 (B = 0.18, SE = 0.13; 95% CI = 0.08 to 0.44, p = 0.17), ACQ2 (B = 0.77, SE = 0.53; 95% CI = −0.27 to 1.82, p = 0.15), or AUDIT Score (B = 0.20, SE = 0.18; 95% CI = 0.16 to 0.56, p = 0.28).
