Chunk #21 — Materials and methods — Cohort level analysis

Source

A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.

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For the QIMR sample, the most probable imputed genotype at each SNP was tested for association with the four TPQ scales using a family-based association test,32 which takes family relationships into account (including identical twins). The additive genetic effect was calculated.