To assess the power of our current approach, we use current sample sizes and standard deviations, the program PS v2.1.31 [35,36] and α = 0.05. To provide controls for the possibilities that abuser-control differences observed herein were due to a) occult ethnic/racial allele frequency differences or b) noisy assays, we assessed the overlap between the results obtained here and the SNPs that displayed the largest a) allele frequency differences between African-American vs European-American control individuals and b) the largest assay "noise".
