either the allele frequencies or on the disequilibrium parameter D=p11−p12, which (as with f) is subject to awkward constraints; these authors used numerical integration to obtain the posterior distribution. Ayres and Balding (1998) considered estimation for the fixation indices model, with inference carried out using Markov chain Monte Carlo (MCMC). Montoya-Delgado et al. (2001) use the Bayes factor as a test statistic. Consonni, Gutierrez-Pena, and Veronese (2008) discuss various methods for choosing “compatible” priors for nested models, with particular reference to the HWE model.
