The intracranial, one-dimensional CSD has been empirically validated as a method for identifying ERP generators at an sublaminar scale (Mitzdorf, 1985; Schroeder et al., 1995). In addition to cortical generators, a one-dimensional CSD is directly applicable to other laminated structures as well (e.g., inferior colliculus, Muller-Preuss and Mitzdorf, 1984; lateral geniculate nucleus, Schroeder et al., 1989). In all cases, CSD sinks indicate local depolarization (current removed from the extracellular medium), while sources indicate local return currents and neuronal hyperpolarization (current injected into the extracellular medium).
