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Chunk #19 — METHODS — Twin Modeling

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Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms.
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report greater AD symptomatology?).3 parameters, X, Y and Z, which represent the change in A, C and E respectively as a function of changing age at 1st drink. If the effect of X is significant (represented by a Δχ2 greater than 3.84 for 1 degree of freedom), then there is evidence for gene x environment interaction (i.e. heritability of AD symptoms varies as function of age at 1st drink).