Determining which adolescents are more susceptible to the addictive nature of nicotine would be a critical step towards the development of personalized prevention and cessation interventions. The goal of this study was to examine the associations between the rate of nicotine metabolism and cigarette consumption, addiction and withdrawal symptoms in a sample of adolescent light smokers. We hypothesized that among adolescent light smokers slower metabolizers will smoke fewer cigarettes, have less evidence of addiction and will experience fewer withdrawal symptoms compared to faster metabolizers.
