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Chunk #36 — Materials and Methods — Utilizing Expression Information in GWAS

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Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS.
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We then ordered the SNPs according to their score S from largest to smallest score. The top SNPs based on the eQTL score show an excess of small association p-values with Crohn's disease (for example, in the top ten SNPs, six have p-values smaller than 0.01).