alcohol in our sample. This is in line with our findings because we only found a direct effect of the GG genotype on adolescent alcohol problems. Note, however, that the GABRA2 risk alleles were inconsistent in the prior studies on positive subjective response as well. Therefore, these are merely possibilities and other mechanisms might be responsible, which might be the topic of future research. The present results are consistent with previous theories proposing that GABRA2 confers risk for a spectrum of externalizing problems [27], and indicate that this risk might operate through more than one mechanism.
