Chunk #22 — Materials and Methods — Smoking-related diseases — Abdominal aortic aneurysm

Source

A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences.

Embedded

yes

Text

Whole-genome sequencing and SNP calling SNPs were imputed based on whole-genome sequence data from about 2636 Icelanders, selected for various neoplastic, cardiovascular, metabolic and psychiatric conditions. The sample preparation, DNA-sequencing methodology, alignment and BAM file generation have been described previously.21