Chunk #7 — Genome-wide linkage studies
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on linkage analysis in a set of 474 small families recruited in Ireland. The strongest results from this study (up to a multipoint lod score of 4.59) were also on chromosome 4. In the only genomewide linkage study of AD in an African-American (AA) population, we found genomewide-significant linkage to markers on chromosome 10 (Gelernter et al. 2009).