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Chunk #7 — 2. Goals of replication — 2.i. Convincing statistical evidence for association

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Replication in genome-wide association studies.
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this ratio. [13]) The posterior odds of true association given the data are equal to the Bayes Factor times the prior odds of association. In Figure 1 the dashed line represents the Bayes Factor needed to achieve posterior odds for association of 3:1, assuming prior odds of association of 1:99,999 (i.e. roughly 100 out of 10,000,000 variants are truly associated with the studied trait).