Chunk #24 — METHODS — Gene and Gene-Set Tests.

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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.

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For each phenotype, we used SEQMINER68 and the UCSC genome browser annotations (refGene; retrieved December 15 2017) to annotate all conditionally independent genome-wide significant variants. We identified all genes (all variants 5’ to 3’ UTR) harboring at least one variant within LD r2>0.3 with any conditionally independent variant. See Supplementary Tables 1–5.