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Chunk #21 — Online methods — Details of imputation, association testing and replication in the InCHIANTI study

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A reference panel of 64,976 haplotypes for genotype imputation.
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A total of 93 circulating factors available in the InCHIANTI study were double inverse-normalised, while adjusted for age and sex, prior to association testing14,15. Association analysis was performed using a linear mixed model framework as implemented in GEMMA (see URLs). Plots of association in Figure 2 were produced using LocusZoom (see URLs).