We went on to perform the structured multivariate GWAS analyses using two factor models: the correlated factors model (with Factors 1-4 as the GWAS target) and the hierarchical factor model (with the higher order p-factor as the GWAS target; Fig. 6, Supplementary Fig. 32 for QQ-plots, and Supplementary Fig. 33 for bar plots of individual variants estimated as genome-wide significant). We also estimate QSNP specific to each factor used as a GWAS target (see Methods for details).
