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Chunk #10 — Results — SNP fine mapping on chromosome 2q

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COGA phenotypes and linkages on chromosome 2.
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We used the program FBAT to examine evidence for association between SNP genotypes and each of the outcome variables of interest. There were a total of ten phenotypes of type Ai_j, and the two principal component derived phenotypes mentioned above (EEG, and alcoholism/latent). Each association can be tested using either a dominant model for mode of inheritance (i.e., one allele or haplotype dominant over all other alleles or haplotypes), or an additive model (i.e., risk increasing additively with each addition copy of the allele or haplotype). Thus, for a given SNP, up to a total of 24 association tests can be significant. Figure 7 shows the number of significant associations that were found for each SNP in this region by SNP position in centimorgans.