Chunk #137 — Quantification and Statistical Analysis — Replicate Correlation (CC)

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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

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Each L1000 experiment consists of multiple biological replicates. To derive an aggregate measure of replicate reproducibility, we compute the 75th quantile of the Spearman correlations between all pairwise combinations of replicate level 4 profiles for a given experiment.