Chunk #56 — Locomotor Activating, Autonomic and Central Electrophysiological Responses to Alcohol Predictive of Risk — Heart rate and autonomic stimulation
addition, Native Americans at high risk for alcoholism were not found to have increases in heart rate following an alcohol challenge (Garcia-Andrade et al. 1997) and, not unexpectedly, increased heart rate following an alcohol challenge was found to be highly associated with “feeling terrible” in Asian men with the ALDH2*2 allele [c.f. (Wall et al. 1992)]. Overall, it is not clear to what extent these heart rate measures may share genetic risk factors with other measures of intoxication (Conrod et al. 2001;Ray et al. 2006). Nevertheless, heart rate changes may provide a useful model to explore in rodents.
