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Chunk #58 — 4. Discussion — 4.3 Alcohol effects and family history of alcoholism

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Response to alcohol in women: role of the menstrual cycle and a family history of alcoholism.
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While FHP women reported somewhat more dysphoric mood effects than FHN women at baseline, these differences were observed primarily during the luteal phase. Further, the range and magnitude of symptoms was less pronounced than has been previously reported in other studies that did not control for menstrual cycle phase (Ciraulo et al., 1996; Evans et al., 2000; Evans and Levin, 2003), or were conducted primarily in FHP and FHN men (e.g., Moss et al., 1989; de Wit and McCracken, 1990). For instance, in one of our previous studies (Evans and Levin, 2003), FHP women differed from FHN women at baseline on most of the POMS subscales. It is unclear why FHP women in the present study reported less dysphoric mood. One possibility is that in the present study FHP women drank significantly more than FHN women (6.1 vs 1.9 drinks/week) compared to our previous study (Evans and Levin, 2003), although none of the women had an alcohol used disorder. This increase in alcohol consumption among the FHP women could simply reflect the general increase in alcohol consumption among women in