Chunk #24 — Results — Drug-Free Genotype Differences—Stop Task — The ZKPQ

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Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants.

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This analysis included only 86 participants because the questionnaire was added later in the study. In this subset, genotypic groups of the individual 12 DRD2 loci were similar on the demographic variables included in this study. Of the 12 SNPs, 2 showed nominally significant differences on the Impulsivity/Sensation Seeking subscale of the ZKPQ (rs4648317 and rs12364283—both in Haplotype Block 2; see Table 3). However, the two SNPs did not remain significant after adjusting for multiple testing (see Table 4).