paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #35 — Methods — Simulation — Parameter settings

Source
Dosage transmission disequilibrium test (dTDT) for linkage and association detection.
Embedded
yes

Text

f or g: penetrance of disease genotype DiDi or DiDj, where i or j = 1 or 2 and i ≠ j. To simplify the notation, here we use f to denote f 11 and g to denote f 12 or f 22. As noted, we separate the disease models as dominant (f, g, g), recessive (f, f, g), and co-dominant (f, 0.5g, g) where f = 0.0, 0.1K, 0.3K, 0.5K, 0.7K, or 0.9K and g = 1.1K, 0.5, 0.7, 0.9, or 1.0.