Chunk #22 — Materials and Methods — Statistical analyses

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Genome-wide time-to-event analysis on smoking progression stages in a family-based study.

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We further conducted fixed‐effect meta‐analyses for the top five SNPs based on the effect sizes and standard errors from the discovery and replication studies using GWAMA (http://www.well.ox.ac.uk/gwama). P‐values below 5e‐08 were considered statistically significant.