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Chunk #2 — Methods and Materials — Identification of Lifetime Trauma Exposure and PTSD Diagnosis

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Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
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In the PTSD section of the interview, 12 types of traumatic events were assessed: experienced direct combat in a war; seriously physically attacked or assaulted; physically abused as a child; seriously neglected as a child; raped; sexually molested or assaulted; threatened with a weapon; held captive or kidnapped; witnessed someone being badly injured or killed; involved in a flood, fire, or other natural disaster; involved in a life-threatening accident; suffered a great shock because one of the above events happened to someone close to you; and other. Participants were asked to list up to three traumatic events and describe the trauma in detail. Those reporting traumatic experiences were then interviewed for potential PTSD symptoms. After the data were scored, PTSD diagnoses were generated based on DSM-IV criteria. The interrater and test-retest reliability (κ) of the PTSD diagnosis using the SSADDA were .59 and .76, respectively (21).