We created a second version of this simulated dataset by first removing individuals from the Val Borbera dataset such that no pair of individuals had a genome wide relatedness in the remaining data. This reduced the dataset from 1071 to 778 individuals (440 females and 338 males) allowing us to simulate a dataset with 84 mother-father-child trios, merged together with the original 440 females. By removing closely related individuals from the cohort we create a simulated dataset more like a non-isolated population. Detection of recombination events will be harder in this setting due to reduced levels of IBD sharing.
