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Chunk #36 — Discussion

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A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.
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Several SNPs identified as candidates in a previously reported meta-analysis and GWAS of alcohol consumption also showed nominal evidence of replication in the present study. Statistics for the SNPs that showed the strongest association with alcohol consumption in previous studies were extracted from the present meta-analysis. SNPs in autism susceptibility candidate 2 (AUTS2) (Schumann et al. 2011), inaD-like (INADL), chromosome 15 open reading frame 32 (C15orf32), and huntingtin interacting protein (HIP1) (Heath et al. 2011) were nominally associated with maxdrinks ( p < 0.05) in the present dataset.