Chunk #53 — Methods — RNA-seq integration and visualization

Source

Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder.

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To visualize all cells in the same plot, we converted each pool to an on-disk BPCells matrix79. This allowed us to merge each object in a memory-efficient way. After merging, the function RunUMAP was run on the combined object for 2D visualization.