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Chunk #8 — Recent discoveries on the molecular genetics of alcohol use behaviors

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Recent Efforts to Dissect the Genetic Basis of Alcohol Use and Abuse.
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Table 1 summarizes the most recent GWAS of alcohol use behaviors (N = 16); Figure 2 provides an overview of the chronology of these studies. Figure 3 shows that the list of genes identified by these studies is highly heterogeneous. These data suggest incomplete genetic overlap between measures of alcohol use behaviors (Figure 4), though ascertainment bias and limited power (see Figure 5) are likely to be additional contributing factors.