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Chunk #28 — 3 Results — 3.2 Traditional fMRI Analysis

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Simultaneous EEG-fMRI reveals a temporal cascade of task-related and default-mode activations during a simple target detection task.
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Event-related BOLD responses to target stimuli were present in multiple brain areas, including bilateral supramarginal gyri, insular cortices, cingulate cortices, angular gyri, precentral gyri, thalamus, cerebellum, and brainstem. Postcentral activations were strong and left-lateralized, consistent with right-handed button press. These activations matched previous visual oddball paradigm results (Laurens et al., 2005; Stevens et al., 2000; Warbrick et al., 2009), and were even stronger and more widespread in the traditional event-related target vs. standard contrast (Supplementary Figure 2). This contrast additionally resulted in right-lateralized clusters in precuneus and middle frontal gyrus. RT-variability statistical maps (Supplementary Figure 3) showed activations in anterior cingulate cortex (ACC), supplementary motor area, and right precentral gyrus.