Accordingly, several fMRI studies have shown that IGD patients exhibit dysfunction within reward circuits. For example, Ding et al. found that adolescents with IGD show increased PCC connectivity relative to HCs and that this PCC connectivity is correlated with the severity of IGD symptoms47. Similarly, individuals with IGD exhibit greater brain activation in reward processing-related regions, such as the dorsolateral prefrontal cortex, PCC, anterior cingulate cortex, and precuneus, in response to gaming cues compared to HCs48. In the present study, gamma coherence in the fronto-central area predicted the IAT scores in all groups. Taken together, the present findings concerning increased gamma coherence in IGD patients during the resting-state indicate that their behavioral changes may be related to an abnormal excitatory system and dysfunctional reward-sensitive responses. Future EEG studies using source localization and/or an integrative approach in conjunction with other methods are needed to clarify the roles of gamma synchrony and the DMN in IGD.
