the starting clique. We selected a glom factor of 0.7 for the analyses presented here, which maintains an edge density >90% in nearly all the resulting paracliques. For such defined paracliques, probe-sets had expression responses to ethanol correlated with at least 70% of the other paraclique members at a threshold ≥|0.7|. Lowering the glom factor below 0.7 resulted in a sharp drop-off in edge density. Furthermore, empiric testing showed that more stringent glom factors produced similar overall functional results but tended to fragment known correlated gene groups (e.g. dopamine signaling genes) into multiple paracliques (data not shown).
