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Chunk #4 — Introduction

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A population-based twin study of the genetic and environmental relationship of major depression, regular tobacco use and nicotine dependence.
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We address several questions: (i) is there evidence of a shared liability, or non-causal explanation, for the association between MD, tobacco use and ND?; (ii) does the structure of genetic and environmental influences on these traits differ between males and females?; (iii) in males, are there differences between genetic and environmental influences on cigarette use versus snus use and corresponding measures of ND?