paperKB
coga / coga-kb
Help
Sign in

Chunk #45 — Gene network inference within individuals using cross-tissue expression variation — Personal transcriptomics and implications for human disease

Source
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans.
Embedded
yes

Text

The in-depth analysis of multitissue transcriptomes enables both an understanding of the population-level properties of the transcriptome as well as individual level properties inferred from analyses of single transcriptomes or the transcriptomes of multiple tissues from a single individual. As is the case for personalized genomics, this individual-level transcriptome analysis is likely to become a crucial addition to the personalized assessment of an individual’s biology and likely disease status.