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Chunk #7 — MATERIALS AND METHODS — Assessments

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Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis.
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Phenotypic information was obtained through administration of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA), a computer-assisted interview comprised of 26 sections (including one for cocaine use and related behaviors) that yields lifetime DSM-IV diagnoses of substance use and Axis I psychiatric disorders, as well as antisocial personality disorder [Pierucci-Lagha et al., 2005, 2007]. The test–retest and inter-rater reliabilities of the SSADDA DSM-IV diagnosis of CD were excellent, with κ = 0.92 and 0.83, respectively [Pierucci-Lagha et al., 2005].