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Chunk #27 — Results — Differentially expressed miRNAs in multiple brain regions of AUD subjects and ethanol-exposed hESC-derived cortical interneurons

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Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks.
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Venn diagrams were made to display the number of differentially expressed miRNAs (P < 0.05) shared between eight brain regions of AUD subjects (Set 1 and Set 2) and ethanol-exposed hESC-derived cortical interneurons (Fig. S8). The in vitro cellular model study confirmed several AUD-associated brain miRNAs, including miR-98-3p (in AMY and HIP), miR-508-5p (in AMY), miR-548ah-3p (in CRB), miR-548p (in CRB), miR-486-5p (in PFC), miR-486-3p (in PFC), miR-139-3p (in PFC), and miR-151a-5p (in PFC).