With regard to changes in CB1 receptor expression, chronic corticosterone does not alter number or affinity of CB1 receptors in the amygdala of rats (Hill et al., 2005). Furthermore, neither chronic restraint stress in mice (Rademacher et al., 2008) nor chronic unpredictable stress in rats alters CB1 receptor number or affinity in the amygdala (Hill et al., 2008).
