All participants were free of the following study exclusions: (1) medical diagnoses of cancer, stroke, diabetes requiring insulin treatment, chronic kidney or liver disease, or lifetime history of psychotic symptoms; (2) use of psychotropic, glucocorticoid, or hypolipidemic medication; and (3) conditions affecting cerebral blood flow and metabolism (e.g., hypertension). Diagnosis of any current DSM-IV Axis I disorder or select Axis II disorders (Antisocial Personality Disorder and Borderline Personality Disorder), assessed with the electronic Mini International Neuropsychiatric Interview18 and Structured Clinical Interview for the DSM-IV (SCID) subtests19, respectively, were not an exclusion as the DNS seeks to establish broad variability in multiple behavioral phenotypes related to psychopathology. However, all participants were medication-free at the time of the study. No participants met criteria for either Antisocial or Borderline Personality Disorder, and 16 participants from our final sample (N = 80) met criteria for at least one Axis I disorder. Since the exclusion of these individuals did not substantially alter our results, we present data from the entire sample in the main text (specific diagnoses available upon request). In addition, all analyses were
