Chunk #18 — Model — Gene Frequency Distributions

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Data and theory point to mainly additive genetic variance for complex traits.

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Uniform: f(p) = 1, assuming N is sufficiently large that the discreteness of the distribution and any non-uniformity as p approaches 1 or 0 can be ignored, i.e. integrated over 0 to 1. This and the ‘U’ gene frequency distributions are, for simplicity, assumed to be continuous.