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Chunk #12 — Results

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Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.
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The interaction between sex and SNP effects on growth was investigated due to differences in growth parameters (see Table 1). We did not observe any statistically significant sex-SNP interactions on any of the outcomes after Bonferroni correction (at p<0.0011 level). The smallest p-value was observed for SNP rs2814933 (C6orf106) which could be associated with timing of pubertal growth spurt in males (age at PHV2 beta = 0.16 years) while in females there is no effect (age at PHV2 beta = −0.003 years; sex interaction p = 0.003). Due to only few interactions that were not significant after Bonferroni correction, the results are shown as sex-adjusted for all SNPs in Table 2.