Culture with neither the reducing agent β-mercaptoethanol nor the mood stabilizer valproic acid, which was previously reported to reduce increased extra-mitochondrial oxygen consumption in SZ hiPSC neural cells,17 was capable of ameliorating aberrant migration of SZ neurospheres (264 total SZ neurospheres were analyzed relative to 262 total control neurospheres; P>0.7) (Figure 4d).
